Green synthesis, antimicrobial effects of Ag@HAp nanoparticles using Perilla leaf extract
Abstract
Nano hydroxyapatite (HAp) has been shown to be a bone replacement and repair agent and has biological compatibility. In this work, hydroxyapatite nanoparticles were synthesized from eggshell, the diameter of it after testing the reaction conditions of about 32,58 nm. The structural and morphological characteristics of HAP were carried out by X-ray diffraction, Fourier transform infrared (FT-IR). Hydroxyapatite doped silver (Ag-HAp) is obtained by the green synthetic pathway. Silver dopant nanoparticles (AgNPs) were obtained by biosynthesis based onPerillaleaf extract, the diameter of nanoparticle about 24,22 nm. This study focused on the characteristics and use of non-toxic, environmentally friendly andantibacterial ability Ag-HAP nanoparticles. Potential application in many areas, such as tissue engineering, bone repair as well as protein.
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